Dr. med. Dirk Manski

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Renal Cell Carcinoma: Definition and Epidemiology

Definition of Renal Cell Carcinoma

Renal cell carcinoma is the most common malignant tumor of the kidney arising from different epithelial parts from the nephron. Review literature: (Ljungberg et al, 2010).

figure surgical specimen of renal cell carcinoma

Surgical specimen of a clear cell renal cell carcinoma: typical yellow-brown cut surface and distinct separation from the normal kidney tissue. Public domain image of Dr. Edwin P. Ewing, Public Health Image Library, Centers for Disease Control and Prevention, USA, www.cdc.gov.

Epidemiology of Renal Cell Carcinoma

Cancer statistics:

Mortality of renal cell carcinoma:

Mortality is declining, 2018 figures for Germany are 5/100.000 for men and 2/100.000 for women.

Incidence of renal cell carcinoma:

Incidence of RCC in Germany (2018): 15/100.000 for men and 8/100.000 for women. Rising incidence with age, peak incidence at 70–75 years, but RCC can also occur in children.

Tumor stage:

The majority of kidney tumors are diagnosed in stage T1 and T2. Advanced T4 tumors are rare at first presentation (2%).

Index: 1–9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z


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