Dr. med. Dirk Manski

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Alpha-Blocker (1/6): General Side Effects and Contraindications

Review Literatur: (Chapple, 2004).

Alpha-Blocker: General Mechanism of Action

Postsynaptic alpha1-blockade leads to:

Side Effects of Alpha-Blocker

Contraindications of Alpha-Blocker

Urological Contraindications:

Conservative treatment of BPH is not indicated, if surgical treatment is imperative: chronic urinary retention with renal failure, recurrent hematuria due to prostatic enlargement, recurrent infections or bladder stones.

Cardiac Contraindications:

Hypotension, mechanical heart failure (valvular, pulmonary embolism, pericarditis), congestive heart failure.

Other contraindications:

Severe liver insufficiency. Alpha-blocker should be paused perioperatively for cataract surgery to prevent an intraoperative floppy iris syndrome.

Drug interactions

Do not combine two alpha-blocker for better treatment effect.

Index: 1–9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z


Chapple 2004 CHAPPLE, C. R.:
Pharmacological therapy of benign prostatic hyperplasia/lower urinary tract symptoms: an overview for the practising clinician.
In: BJU Int
94 (2004), Nr. 5, S. 738–44

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