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Diagnosis and Treatment of Renal Artery Aneurysm
Definition of Renal Artery Aneurysm
A renal artery aneurysm is an increase in the renal artery diameter to more than 1.5 times the normal vessel diameter, which is classified according to the specific morphology:
True aneurysm:
An outpouching involving all layers of the vessel wall; the morphology may be asymmetric and saccular or uniformly cylindrical. As dilation progresses, the stability of the arterial wall decreases. True aneurysms account for the majority of renal artery aneurysms.
Pseudoaneurysm or false aneurysm:
A false aneurysm (pseudoaneurysm) results from injury to the vessel wall, most commonly iatrogenic, traumatic, or inflammatory, with formation of a pulsatile extravascular hematoma that remains in arterial communication.
Dissecting aneurysm:
An intimal tear allows blood flow between the layers of the vessel wall, resulting in aneurysmal dilation.
Arteriovenous aneurysm:
Aneurysmal changes arising from an arteriovenous fistula of the renal vessels.
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Epidemiology
1:300 to 1:1000, most of them without the need for therapy. Rupture of a renal artery aneurysm is rare, with a mortality rate of around 10%. In the event of rupture during pregnancy, maternal and fetal mortality are substantially higher.
Etiology of renal artery aneurysm
Congenital, atherosclerosis, fibromuscular dysplasia, traumatic, postinterventional (iatrogenic), vasculitides.
Signs and Symptoms
Many renal artery aneurysms are asymptomatic incidental findings. Possible symptoms include arterial hypertension, pain, hematuria, a pulsatile abdominal mass (rare), or an abdominal bruit. Hypotension, shock, and an acute abdomen may result from aneurysm rupture.
Diagnostic Workup of Renal Artery Aneurysm
- Doppler Ultrasound: Serves as an initial screening examination; however, its diagnostic accuracy depends on the examiner and the anatomic conditions.
- CT Angiography: Noninvasive imaging modality for diagnostic confirmation, size assessment, evaluation of calcification, and treatment planning.
- MR Angiography: An alternative in patients with contraindications to iodinated contrast media or when repeated follow-up imaging is required.
- Catheter Angiography: The invasive gold standard for detailed vascular delineation, particularly when endovascular treatment is planned.
Treatment of Renal Artery Aneurysm
The indications for endovascular procedures (stent placement) or open surgical treatment (excision and reconstruction of the renal artery) are:
- Diameter >2.5–3 cm
- Pseudoaneurysm at risk of rupture.
- Symptomatic lesion with flank pain, hematuria, renin-dependent hypertension, or clinically significant embolization.
- Rapid increase in size during follow-up; incomplete circumferential calcification is an additional risk factor.
- Impending pregnancy increases the risk of rupture.
- Arteriovenous fistula.
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Index: 1–9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
References
Nosher, J. L.; Chung, J.; Brevetti, L. S.; Graham, A.
M. & Siegel, R. L.
Visceral and renal artery aneurysms: a pictorial
essay on endovascular therapy.
Radiographics, 2006,
26, 1687-704; quiz 1687.
Deutsche Version: Aneurysma der Nierenarterie
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