Dr. med. Dirk Manski

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Ask-Upmark Kidney: Etiology and Symptoms

Definition of the Ask-Upmark Kidney

The Ask-Upmark kidney is a segmental hypoplasia of the kidney often caused by vesicoureteral reflux (VUR).


The Ask-Upmark kidney is the result of vesicoureteral reflux and chronic pyelonephritis. Segmental hypoplasia with scarring of the renal parenchyma leads to renin release, secondary hyperaldosteronism and arterial hypertension.

Signs and Symptoms of the Ask-Upmark Kidney

Treatment of Ask-Upmark Kidney

Unilateral Ask-Upmark kidney with severe hypertension is treated with nephrectomy. Medical treatment of arterial hypertension and chronic kidney disease is crucial for bilateral disease.

Index: 1–9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z


E. Harnisch, T. Leertouwer, K. Cransberg, and J. E. Kist-van Holthe, “A 3-year old girl with seizures, hypokalemia and metabolic alkalosis.,” BMJ case reports, vol. 2010, 2010.

  Deutsche Version: Ask-Upmark Niere