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Urethral Atresia
Urethral atresia is a rare malformation of the urethra, which is often lethal. The disease corresponds to the maximum variant of a posterior urethral valve, and the lack of urine excretion results in oligohydramnios, bilateral hydronephrosis, and megacystis. Survival with urethral atresia is possible with an open urachus or prenatal placement of a vesico-amniotic shunt. Still, end-stage renal disease and multiple reconstructive operations have to be expected (Gonzales, 2001).
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References
González, R.; Filippo, R. D.; Jednak, R. & Barthold, J. S. Urethral atresia: long-term outcome in 6 children who survived the neonatal period.J Urol, 2001, 165, 2241-2244.
Deutsche Version: Atresie der Harnröhre