Dr. med. Dirk Manski

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Fetal and Congenital Megacystis


Congenital megacystis is an enlarged bladder with massive vesicoureteral reflux of various etiology. In the first trimester, fetal megacystis is most commonly defined as a longitudinal bladder dimension of over 7 mm. Later in pregnancy, megacystis refers to a sagittal bladder diameter (in mm) greater than gestational age (in weeks) + 12 (Taghavi et al., 2017).


The prevalence of megacystis is around 1:1500 in the first trimenon.


Many syndromes and diseases lead to megacystis:


Oligohydramnios, lung hypoplasia, and intestinal obstruction confer a poor prognosis.


See treatment of vesicourethral reflux and posterior urethral valves.

Index: 1–9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z


Mandell, J.; Lebowitz, R. L.; Peters, C. A.; Estroff, J. A.; Retik, A. B. & Benacerraf, B. R. Prenatal diagnosis of the megacystis-megaureter association.
J Urol, 1992, 148, 1487-1489

Puri, P. & Shinkai, M. Megacystis microcolon intestinal hypoperistalsis syndrome.
Semin Pediatr Surg, 2005, 14, 58-63

K. Taghavi, C. Sharpe, and M. D. Stringer, “Fetal megacystis: A systematic review.,” J. Pediatr Urol, vol. 13, no. 1, pp. 7–15, 2017.

  Deutsche Version: Megazystis