Dr. med. Dirk Manski

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Multicystic Dysplastic Kidney (MCDK)

Definition of Multicystic Dysplastic Kidney (MCDK)

Multicystic dysplastic kidney (MCDK) is a severe form of congenital kidney malformation characterized by renal noncommunicating cysts and the absence of a normal pyeloureteral system (Hains et al., 2009).


The incidence is 1:4300 live births. Multicystic renal dysplasia is the most common abdominal tumor in the neonatal period and the most common cystic lesion of the kidney in childhood.


The etiology is unclear, there are several theories explaining a multicystic dysplastic kidney:

Most cases of multicystic renal dysplasia are subject to spontaneous involution.

Signs and Symptoms of Multicystic Renal Dysplasia

Diagnostic Workup in MCDK

Treatment of Multicystic Renal Dysplasia

Perform ultrasound imaging, blood pressure test, and creatinine every 6–12 months until the age of 8 years or until involution of multicystic renal dysplasia. Perform nephrectomy if the kidney is causing symptoms (flank pain, infections, hypertension) or if the mass is suspicious for malignancy.

Index: 1–9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z


Hains, D. S.; Bates, C. M.; Ingraham, S. & Schwaderer, A. L. Management and etiology of the unilateral multicystic dysplastic kidney: a review.
Pediatr Nephrol, 2009, 24, 233-241.

  Deutsche Version: Multizystische Nierendysplasie