Dr. med. Dirk Manski

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Fundamentals and Symptoms of Megacalycosis


Megacalycosis is the enlargement of the calyceal system without urinary tract obstruction or vesicoureteral reflux, which is caused by a malformation of the renal papillae.


male:female = 6:1

Etiology of Megacalycosis:

Megacalycosis caused by a malformation of the renal medulla with short collecting ducts, the number of calyces is increased.

Pathophysiology of Megacalycosis:

Megacalycosis causes a mild disturbance of the maximum concentration capacity of the kidney, the long term prognosis in relation to renal function is good.

Signs and Symptoms:

In general, no complaints.

Diagnostic Work-Up of Megacalycosis

Intravenous Urography:

Intravenous urography shows a enlargement of the pyelocalyceal system and an increased number of calyces. Dilatation of the renal pelvis ist not present, the ureter is slim [fig. megacalycosis in intravenous urography].


Vesicoureteral reflux is not present in voiding cysturethrography.

Renal Scintigraphy:

Normal renal function, prompt washout of the radionuclide.

megacalycosis as seen in intravenous urography  

Megacalycosis: intravenous urography shows an increased number and dilation of the calyces. With kind permission of Dr. G. Antes, Kempten.

Treatment of Megacalycosis

Specific treatment is not necessary.

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  Deutsche Version: Megakalikose