Dr. med. Dirk Manski

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Fundamentals and Symptoms of Megacalycosis


Megacalycosis is the enlargement of the calyceal system without urinary tract obstruction or vesicoureteral reflux caused by a malformation of the renal papillae.


male:female = 6:1

Pathophysiology of Megacalycosis:

The malformation of the renal medulla leads to short collecting ducts and an increased number of calyces. Megacalycosis causes a mild disturbance of the maximum concentration capacity of the kidney, the long term prognosis in relation to renal function is good.

Signs and Symptoms:

In general, no complaints.

Diagnostic Workup of Megacalycosis

Intravenous Urography:

Intravenous urography shows an enlargement of the pyelocalyceal system and increased calyces. There is no ectasia of the renal pelvis and ureter [fig. Megacalycosis in intravenous urography].


No vesicoureteral reflux in voiding cystourethrography.

Renal Scintigraphy:

Renal scintigraphy reveals sormal renal function with rapid washout of the radionuclide.

megacalycosis as seen in intravenous urography
Megacalycosis: intravenous urography shows an increased number and dilatation of the calyces. With kind permission, Dr. G. Antes, Kempten.

Treatment of Megacalycosis

Specific treatment is not necessary.

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  Deutsche Version: Megakalikose