Kidney Dysplasia
Definition of Renal Dysplasia
Kidney dysplasia is a congenital malformation of the kidney. The disturbed metanephric development leads to primitive structure elements (immature or primitive glomeruli and tubuli...), often accompanied by hypoplasia. The risk for renal failure depends on the severity of (bilateral) kidney dysplasia. Kidney dysplasia can be categorized depending on the comorbidities and etiology:
- Renal dysplasia
- Renal hypodysplasia with normal ureteral orifice (with or without obstruction)
- Renal hypodysplasia with abnormal ureteral orifice (lateral or caudal ectopia)
- Renal hypodysplasia with urethral (subvesical) obstruction
- Renal hypodysplasia in Prune-belly syndrome
Etiology of Kidney Dysplasia
- impaired ureteric budding
- fetal or postpartal obstruction of the urinary tract
Pathology of Renal Dysplasia
Pathologic signs of renal dysplasia are primitive tubules, lined by epithelium and surrounded by concentric rings of smooth muscle cells and connective tissue. Often, cartilage is found in the specimen of kidney dysplasia.
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Dr. med. Dirk Manski
man...@urologielehrbuch.de