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Penile Tumor: Differential Diagnosis

Benign Penile Tumors

• Genital ulcers: syphilis, chancroid, genital herpes, granuloma inguinale and lymphogranuloma venereum.
• Viral infections: genital herpes, condyloma acuminatum.
• Lichen sclerosus (Balanitis xerotica obliterans)
• Leukoplakia: white patches usually as a result of chronic irritation. Histological criteria for leukoplakia are hyperkeratosis, parakeratosis and dermal edema.
• Epidermoid cyst is caused by scattered epidermal cells which produce an elastic tumor under the skin. The wall of an epidermoid cyst has a thin layer of squamous epithelium.
• Retention cysts are caused by the blockage of a duct of sebaceous glands. They are found congenital near the raphe or are acquired after circumcision or trauma.
• Diseases of the penile shaft: Peyronie disease, thrombophlebitis (Mondor's disease), fibromas, neuromas, Angioma. Scarring after self-manipulation or trauma.

Malignant Penile Tumors

• Precancerous lesions: Bowen disease or erythroplasia of Queyrat
• Verrucous penile carcinoma (Buschke-Löwenstein Tumor)
• Penile cancer
• Basal cell carcinoma
• Kaposi sarcoma, other sarcomas are rare
• Malignant melanoma
• Paget disease
• Lymphoma of the penis
• Urethral carcinoma
• Penile Metastasis

References

  Deutsche Version: Differentialdiagnose Penistumor

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