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Molluscum contagiosum is a viral infection of the epidermis with pearly papules (CDC Guidelines, 2006).
Epidemiology of Molluscum Contagiosum
Risk groups for molluscum contagiosum: children and adolescents, sports with skin-to-skin contact, sexually active persons, patients with immune deficiency.
Etiology of Molluscum Contagiosum
Molluscum contagiosum virus (MCV):
DNA virus of the pox group. Incubation period 2–7 weeks. Transmission from human to human via skin-to-skin contact or via inanimate vectors (e.g. towels).
Signs and Symptoms
- Isolated or grouped dome-shaped skin-colored papules (1–5 mm) with a central umbilication.
- Manifestation at the face, trunk, axillae and genital region.
- Papules can be expressed by lateral pressure (molluscum bodies).
- Generalized manifestation is possible with immunodeficiency.
Diagnosis is possible with inspection only, biopsy is necessary for untypical lesions (virus-infected cells with DNA-containing inclusion bodies).
Treatment of Molluscum Contagiosum
Usually self-limiting disease, which lasts several months to two years. This justifies observation without active therapy. Widespread and persistent disease is possible in patients with immunodeficiency (HIV).
Local application of cantharidin, imiquimod, podophyllotoxin and numerous other substances have been effectively used against molluscum contagiosum. Disadvantages include side effects and high cost.
Curettage followed by iodine-containing disinfection. Alternative techniques: cryosurgery or laser coagulation. Disadvantages include pain and scarring.
Index: 1–9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
- Bikowski 2004 BIKOWSKI, Jr.:
- Molluscum contagiosum: the need for physician intervention and new
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- Center for Disease Control and Prevention.:
- Sexually transmitted diseases treatment guidelines 2006.
2006; 55 (No. RR-11): 1–93.
- Smith und Skelton 2002 SMITH, K. J. ; SKELTON, H.:
- Molluscum contagiosum: recent advances in pathogenic mechanisms, and
In: Am J Clin Dermatol
3 (2002), Nr. 8, S. 535–45
- Ting und Dytoc 2004 TING, P. T. ; DYTOC, M. T.:
- Therapy of external anogenital warts and molluscum contagiosum: a
In: Dermatol Ther
17 (2004), Nr. 1, S. 68–101
- Tyring 2003 TYRING, S. K.:
- Molluscum contagiosum: the importance of early diagnosis and
In: Am J Obstet Gynecol
189 (2003), Nr. 3 Suppl, S. S12–6
Deutsche Version: Molluscum contagiosum: virale Infektion der Haut.