Review literature: (Fonseca u.a., 2000).
Lymphoma of the testis may represent the primary manifestation of extranodal disease or a secondary manifestation of disseminated lymphoma.
5% of all testicular tumors. It is the most common testicular tumor in men over 50 years.
Gross anatomy: diffuse enlarged testicles. Microscopy: all known forms of lymphoma may be possible.
Manifestation in a single lymph node region or a single extranodal organ (=IE).
Manifestation in several lymph node regions or organ regions on one side of the diaphragm.
Manifestation in several lymph node regions or organ regions on both sides of the diaphragm.
Disseminated manifestation in visceral organs.
Testicular enlargement, a quarter of patients report about general symptoms such as weight loss, night sweats and weakness.
Differential blood count, erythrocyte sedimentation rate, LDH, testicular tumor markers.
If histology of the testis reveals lymphoma, the following tests are indicated: bone marrow biopsy, bone scan, CT abdomen and thorax.
Radical inguinal orchiectomy is the first step in diagnosis and therapy. For further treatment of lymphoma, see textbooks of oncology.
If testicular lymphoma is already suspected (before orchiectomy) in disseminated disease, testicular biopsy to confirm the diagnosis is sufficient. Orchiectomy is only necessary due to symptoms.
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Deutsche Version: Lymphom des Hodens
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Dr. med. Dirk Manski
man...@urologielehrbuch.de