Karyotyping: Human Karyotype Analysis
Laboratory Technique of Karyotyping
Karyotyping is the microscopic analysis of the chromosomes of a cell in metaphase, the stage of maximum DNA compression. The chromosomes are numbered according to size and examined. The difference in chromosome staining results from euchromatin and heterochromatin and produces a characteristic banding pattern. The banding pattern of the chromosomes enables identification of individual chromosomes and a possible numerical chromosome aberrations [Fig normal human karyotype].
||Normal human karyotype. Fig. from Public Health Image Library, Center for Disease Control and Prevention, USA, www.cdc.gov.
Urologic Indications for Karyotyping
Karyotyping is indicated for possible disorders of sex development, severe hypospadias, Turner syndrome, Down syndrome or Klinefelter's syndrome.
Index: 1–9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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