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Definition of the Ask-Upmark Kidney
The Ask-Upmark kidney is a segmental hypoplasia of the kidney, which is most often caused by vesicoureteral reflux (VUR).
EtiologyThe Ask-Upmark kidney is the result of vesicoureteral reflux, since vesicoureteral reflux and chronic pyelonephritis are almost always detectable. Dysplasia of the renal parenchyma is also associated.
Segmental hypoplasia with scarring of the renal parenchyma leads to renin release, secondary hyperaldosteronism and arterial hypertension.
Signs and Symptoms of the Ask-Upmark Kidney
- Severe arterial hypertension
- Onset around the 10th year of life
- Hypertensive retinopathy
- Renal insufficiency in bilateral Ask-Upmark kidney
Treatment of Ask-Upmark Kidney
The unilateral Ask-Upmark kidney can be treated with unilateral nephrectomy. With bilateral involvement, medical treatment of arterial hypertension and renal insufficiency is necessary.
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Deutsche Version: Ask-Upmark Niere